BDBM50300124 (5-(phenylsulfinyl)-1H-benzimidazol-2-yl)carbamic acid methyl ester::5-(phenylsulfinyl)-2-benzimidazolecarbamic acid methyl ester::5-phenylsulfinyl-2-carbomethoxyaminobenzimidazole::CHEMBL42442::Fenbendazole sulfoxide::OFDZ::methyl [5-(phenylsulfinyl)-1H-benzimidazol-2-yl]carbamate::oxfendazole

SMILES: COC(=O)Nc1nc2ccc(cc2[nH]1)S(=O)c1ccccc1

InChI Key: InChIKey=BEZZFPOZAYTVHN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50300124   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin D Synthase (Homo sapiens (Human))	BDBM50300124 ((5-(phenylsulfinyl)-1H-benzimidazol-2-yl)carbamic ...) Show SMILES COC(=O)Nc1nc2ccc(cc2[nH]1)S(=O)c1ccccc1 Show InChI InChI=1S/C15H13N3O3S/c1-21-15(19)18-14-16-12-8-7-11(9-13(12)17-14)22(20)10-5-3-2-4-6-10/h2-9H,1H3,(H2,16,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of human H-PGDS expressed in Escherichia coli BL21 assessed as rate of glutathione-chloro-dinitro benzene conjugation				Eur J Med Chem 45: 447-54 (2010) Article DOI: 10.1016/j.ejmech.2009.10.025 BindingDB Entry DOI: 10.7270/Q2HD7VQT
					More data for this Ligand-Target Pair